Eleneon cream contains tretinoin in a concentration of 0.025%.

DESCRIPTION:

• Helps to reduce the number of rashes and the depth of skin lesions in acne.
• Promotes rapid healing of acne rash.
• Promotes skin brightening and rejuvenation.
• Reduces fine lines, roughness and improves skin colour.
• It takes 8 to 10 weeks of use to improve skin condition.
• The greatest effectiveness is achieved with regular use.

APPOINTMENT:

• Skin care for acne.
• Lightening of the skin.
• Rejuvenation of the skin.

HOW TO USE:

• Apply once a day, before bedtime.
• It is possible to start using it at night.
• Before use, wash the skin with a mild detergent and dry it gently.
• Wait 20-30 minutes before applying the cream. Important! The skin should be completely dry to minimise possible irritation.
• Avoid use on mucous membranes, areas around the eyes, mouth, nose, and corners of the nose, as well as on skin areas with open wounds.
• Squeeze no more than 1-1.5 cm of cream onto your fingertip - this should be enough for the entire face.
• Apply the cream to the affected area - first to the forehead, then to the chin and both cheeks.
• After that, spread it evenly over the face, gently rubbing it into the skin.
• The cream should become invisible almost immediately after application.
• If the cream remains visible on the face, reduce the amount of the cream.

RECOMMENDATIONS FOR USE:

• Do not use if you are allergic or hypersensitive to any of the components.
• In case of asthma, consult a doctor before use.
• When using the cream, avoid excessive skin washing, scrubbing, sunlight, tanning beds and ultraviolet light.
• When applying the cream, use a sunscreen with SPF of 15 or higher and wear protective clothing and a wide-brimmed hat covering the treated areas of the skin.
• In case of sunburn, discontinue use of tretinoin cream until the skin has healed.
• Cold weather and wind may irritate the skin treated with tretinoin.
• When applying the cream, avoid contact with lime peel.
• Do not use the cream in case of inflammatory skin conditions, damages, irritations, peeling, redness of the skin, as well as if there is a tumour of the upper skin layer (or if this condition was observed in relatives).
• Do not use the cream during pregnancy or if you are planning a pregnancy.
• If you are breastfeeding, consult your doctor or dermatologist before use.
• Recommended for use by adults and children from 10 years of age.

FULL COMPOSITION:

Cetostearyl alcohol, light liquid paraffin, white soft paraffin, hard paraffin wax, Ginolic CSA (CM-1000), glycerin monostearate, ethylenediaminetetraacetic acid, propylene glycol, butylated hydroxytoluene, sodium methylparaben, sodium propylparaben, USP tretinoin, sodium hydroxide, water.

Elenone cream 0.025%. Conclusion of the State Expertise Centre No. 12.2-18-3/7218 dated 17.11.2022. Not a medicinal product. Advertising of a cosmetic product. Full information is contained in the instructions for use of the cosmetic product. Before use, be sure to read the instructions for use of the cosmetic product and consult your doctor. Keep out of the reach of children. Manufacturer. Elegant Cosmed Pvt. Ltd., Plot No.-32 & 33, GIDC Kuvadav, Rajkot-360023, Gujarat, India. Contact: elegantcosmed.com.

 Official distributor. AVIM GROUP LLC, 3 Oleksiyivska St., Kyiv, tel. 044-361-33-65

It is known that acne is a chronic disease in which periods of exacerbation and remission replace each other. Studies have shown that the number of microcomedones decreases during the use of products and increases after their cancellation. This suggests that it is advisable to use care products for acne constantly: during an exacerbation to put the disease into remission, and in remission to reduce the likelihood of a second exacerbation. What products should be used during an exacerbation and what products should be used during remission?

Retinoids are one of the most commonly prescribed medications for acne.  Retinoids are derivatives of retinol or vitamin A. The effectiveness of retinoids has been proven by numerous studies, so they are included in acne treatment protocols. At the same time, retinoids are multifaceted substances. They have a number of positive effects, one of which is maintaining youthful skin. Therefore, they are also used in anti-ageing cosmetics. At the beginning of using retinoids, you may experience dryness or irritation of the skin, which disappears as the skin adapts to their effects. Dermatologists and cosmetologists widely use such retinoids as tretinoin and adapalene in their practice.

Tretinoin is a representative of the first generation of retinoids. It binds to more receptors on the skin than adapalene. It is quite potent, sometimes causing dryness or irritation of the skin to a greater extent. Among the retinoids, tretinoin is considered the gold standard for anti-ageing cosmetics.

Adapalene is a representative of the third generation of retinoids. It binds to fewer receptors, has a milder effect than tretinoin, causes fewer side effects, and is quite effective.

Dermatologists and cosmetologists select products individually, based on the patient's condition and medical history. One of the acne treatment regimens may include the use of adapalene during acne exacerbation and tretinoin during remission. Thus, during an acute exacerbation, effective control of acne manifestations will be achieved, and the skin will gradually get used to the effects of retinoids. During remission, when the skin has already adapted to retinoids, you can switch to tretinoin - it will maintain remission, and an additional bonus will be its ability to maintain youthful skin.

Sources and literature used:

• Instruction for use of cosmetic product ELENEON cream 0.025%.
• James Leyden et al; Why topical retinoids are the mainstay of acne therapy; Dermatol Ther. 2017 Sep; 7(3): 293-304.
• Koroleva Zh.V., Kalyuzhna LD, Lishchyshina OM, et al; Adap. Acne - an evidence-based clinical guideline, State Expert Centre of the Ministry of Health of Ukraine, 2017.
• L.V. Grechanska, S.P. Ostapenko, Ukrainian Military Medical Academy, Kyiv, Military Medical Clinical Treatment and Rehabilitation Centre, Irpin; Dermatocosmetic preparations as an integral component in the management of patients with acne; Ukrainian Journal of Dermatology, Venereology, Cosmetology, No. 2 (77), 2020.
• Melika Motamedi et al; Clinician's Guide to Topical Retinoids; Journal of Dermatological Medicine and Surgery; Clinician's Guide to Topical Retinoids; First published online 22 July 2021/
• Suleyman Piskin et al; A review of the use of adapalene for the treatment of acne vulgaris; Ther Clin Risk Manag; 2007 Aug; 3(4): 621-624
• С. H. Percy; Safety and efficacy of adapalene gel 0.1% in acne vulgaris: results of a post-marketing surveillance study; https://ijdvl.com
• Daniela Milosesca and co-authors; The use of retinoids in topical anti-aging products: a focused review of clinical data for traditional and nanoproducts; https://link.springer.com; October 2022.